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November 18 2014

rpiitpuapule

Drones Are Taking Pictures That Could Demystify A Malaria Surge



Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

Aerial drones are targeting a new enemy: malaria.

Four hundred feet above a Malaysian forest, a three-foot eBee drone hovers and takes pictures with a 16-megapixel camera every 10 to 20 seconds. But it's not gathering images of the mosquitoes that transmit malaria. Even today's best drones aren't capable of such a photographic marvel. Rather, the drone is looking at a changing landscape that holds clues to the disease's spread.

The malaria drone mission, described in a study published Oct. 22 in Trends in Parasitology, began in December 2013, when UK scientists decided to track a rare strain of the mosquito-borne disease that has surged near Southeast Asian cities. Understanding deforestation may be the key in seeing how this kind of malaria, known as Plasmodium knowlesi, is transmitted.

The mosquitoes that carry P. knowlesi are forest dwellers. The insects breed in cool pools of water under the forest canopy and sap blood from macaque monkeys that harbor the malaria parasite.

In Sabah, Malaysia, human cases of this kind of malaria didn't surface until about 10 years ago, says infectious disease specialist Kimberly Fornace of the London School of Hygiene and Tropical Medicine. She is leading the drone study.

While cases of the most common malaria strains have steadily dropped during this time, P. knowlesi has thrived. It's now the number-one cause of malaria in the region. Fornace and her team suspect that human intrusion into forested areas has created more opportunities for the disease to pass between primates and humans via mosquitoes. The drone imagery they've collected so far suggests there were occasions where land development forced macaques within closer proximity of humans, who then developed malaria.

As part of a project called MONKEYBAR, the team tracks outbreaks by comparing the drone's land surveillance with hospital records of malaria cases. Meanwhile, a local wildlife commission has fitted macaques with GPS collars, which let scientists monitor the locations of monkey troops. Together, this information paints a public health map that explains how land development has influenced monkey movements -- and transmission of malaria to humans. In partnership with Conservation Drones, an organization that builds drones for under $1,000, Fornace and her team plan to build a drone that snaps thermal images of macaques, so the monkeys can someday be identified without GPS collars.

Drones provide a better surveillance picture than satellite images, which are the current standard for mapping environmental changes. But Google Earth images, for example, are only updated every few weeks or months, says parasitologist Chris Drakeley of the London School of Hygiene and Tropical Medicine, who coauthored the Trends in Parasitology study with Fornace. Drones, he says, can provide a more comprehensive, continuous picture: "We avoid cloud cover and can see what the land use was like today, next week and the week after."

The public health implications of drone use extend far beyond malaria, says Harvard epidemiologist Nathan Eagle. Doctors have already used unmanned aircraft to carry medical supplies between rural clinics in South Africa and Haiti. Humanitarian drones also tracked property damage and hunted for survivors after Typhoon Haiyan. And when a disease like Ebola surfaces, a drone could scan for changes in bats' habitats, given that the winged mammals are proposed carriers of the hemorrhagic fever. The prices of these drones are dropping while their specs -- flight performance and cameras -- are improving, says Eagle. All of which means in a few years, a series of very inexpensive aerial vehicles will exist for wider use in public health research.

http://www.npr.org/blogs/goatsandsoda/2014/10/22/357637900/drones-are-taking-pictures-that-could-demystify-a-malaria-surge?utm_medium=RSS&utm_campaign=malaria

November 11 2014

rpiitpuapule

If You Think You'll Never See A Poem About Malaria, You're Wrong



Poet Cameron Conaway (left, in gray cap) visits malaria-hit areas in the Chittagong Tract Hills, Bangladesh, in June 2012. Courtesy of Cameron Conaway hide caption

itoggle caption Courtesy of Cameron Conaway

Poet Cameron Conaway (left, in gray cap) visits malaria-hit areas in the Chittagong Tract Hills, Bangladesh, in June 2012.

Courtesy of Cameron Conaway

Before traveling to Thailand in 2011, American poet Cameron Conaway viewed malaria as many Westerners do: a remote disease summed up by factoids:

It's borne by mosquitoes.

Half the world's population -- 3.4 billion people -- is at risk of catching it.

The disease claims 627,000 lives a year - that's one death every minute.

Conaway, 29, gives a human face to those figures in his new collection, Malaria, Poems. Each poem is paired with a related fact: "roughly one in ten children will suffer from neurological impairment after cerebral malaria" connects to a poem with this line:

"Here / a girl of ten / confused / why her arms won't raise / when she's asked to raise them"

Conaway started writing poetry in 2004, inspired by Lee Peterson, his poetry instructor at Penn State Altoona, who wrote about the Bosnian war. "She taught me that these literary tools weren't just for playing in the sandbox," says Conaway. "They could serve a social purpose."

He came to malaria in a roundabout way. Conaway's trip to Thailand was motivated by a desire to practice Mauy Thai kickboxing (he is a former mixed martial arts fighter and people sometimes call him "the warrior poet"). After he arrived in Bangkok, he met another poet hanging out there, Colin Cheney, who told him about the Wellcome Trust, a global charity that funds health research as well as projects on how culture affects health issues, such as with their features publication Mosaic. The Trust was soliciting applicants for its arts award, so Conaway attended one of the its conferences. There, he met Nick Day, the director of Bangkok's Mahidol Oxford Tropical Medicine Research Unit (MORU), one of the Trust's affiliates.

"I was impressed by Day's ability to talk about malaria and his research in ways that a normal human could understand. He did so with charisma and I really connected with him," says Conaway.

And Conaway learned that malaria has a poetic history. Sir Ronald Ross, who won a Nobel Prize in 1902 for identifying malaria parasites, often wrote poetry about the disease and his discovery:

"With tears and toiling breath / I find thy cunning seeds / O million-murdering death."

With Day's suggestion, Conaway applied for the Trust's arts award and became MORU's first poet-in-residence. He spent seven months traveling to villages and vaccine research centers near Bangkok and in Bangladesh, gathering impressions for his work.

Malaria, Poems was published this month by Michigan State University Press. The poems touch on everything from counterfeit malaria medicines to stillbirths caused by the parasite to traveling bards who perform plays about malaria awareness. He also wrote poems that address social issues such as violence against women in Bangladesh and the lack of medical care in the region.

An excerpt from Malaria, Poems follows and describes Anopheles mosquitoes, which transmit the parasite between people.

SILENCE, ANOPHELES

You should have just asked the mosquito.

-- 14th Dalai Lama

It's risky business needing

(blood)

from others

not for science or even more life

for hellos and goodbyes

and most substances between

but so your kids can exit

while entering and spread

their wings long

after yours dry and carry on

by wind not will.

It's risky business feeding on others,

but we all do

one way or another.

It's risky business needing

when you have nothing,

but life has you and lives

writhe inside you.

Risky to solo into the wild

aisles of forearm hair thicket

for a mad sip,

not quick enough

to snuff the wick of awareness

but too fast for savoring.

A mad sip that makes

you gotcha or gone

and may paint you and yours

and them -- Plasmodium falciparum --

on the canvas you needed

to taste behind.

It's risky business needing

and then getting

and being too too

to know what to do --

too full and carrying

too many to fly.

It's risky business being

the silent messenger

of bad news when you don't know the bad news

is consuming you, too.

It's not risky business

being the blind black barrel

of pistol or proboscis,

but it is damn risky business being

the pointer or the pointed at.

It's risky business being

born without asking

for a beating heart.

Having and then needing to need

to want until next

or else

and sometimes still or else.

Risky when you're expected to deliver

babies and have no gods to guide

their walk on water

because you did it

long before they or him or her or it

never did.

Risky when you're born

on water and capricious cloudscapes

shape whether sun lets leaves

bleed their liquid shadow blankets

into marshes or mangrove swamps

or hoof prints or rice fields or kingdoms

of ditches.

It's risky business naming and being named

while skewered and viewed

under the skewed microscopic lens

of anthropocentrism

an (not) opheles (profit)

a goddess name, Anopheles,

that translates to mean useless

and sounds beautiful at first

then awful when its insides linger.

An(ophel)es, you are only 57% different, no,

you are 43% the same as me, no,

I am, no, we are 43% you, no, we all are

nearly, mostly.

It's risky business leaving

large clues --

a welt and then a dying child slobbering silver

under its mother's croon.

It's risky business being

when you don't

because you have two weeks

or less to do doing.

Risky business killing,

but it depends on who, where, when --

self-sufficient Malawi village in 2014

vs. the legend of Dante & Lord Byron.

Mae Sot or Maine, Rourkela or Leeds.

It's risky business killing

killers that always only want

their kind

of tropical retreat.

It's risky business being

small

profoundly --

the speck of black

sesame or apostrophe

blending in the expanse

of rye or papyrus

and taken

onto allergic tongues.

It's risky business sharing

your body with strangers --

uninvited multiplicities hijacking

what you have

because to them you are what you have.

Risky when all know

your 1 mile per hour,

your under 25 feet high for miles,

your 450 wingbeats per second.

Risky business being you

when some want not to fly

weeks with your wings

but walk days atop them.

Is it riskier business being content

and peacefully going extinct

or not being

content and forever brinking

in the bulbous ends of raindrops

that cling but fatten?

Like raindrops and us, Anopheles,

when you fatten, you fall.

History favors the fallen.

To drip

a long life

of falling

before the fall

or to live

a short life

oblivious to it all?

Risky that we exchange

counters -- DNA mutations

that make some of us

sometimes

sort of

immune to each other's jabs

though hooks always slip through,

and we send each other stumbling,

always stumbling, always only stumbling.

Changing ourselves changes each other.

Each other is ourselves.

They tell us it's risky business doing

being,

but it is more risky being

doing.

Did you hear all that, Anopheles?

How about now?

We're asking. We're good at that.

Does all life listen

at the speed of its growing?

Are we listening too loudly

or too slowly to your silence?

"Human malaria is transmitted only by females of the genus Anopheles. Of the approximately 430 Anopheles species, only 30-40 transmit malaria" (Malaria, Mosquitoes, Centers for Disease Control and Prevention, 8 February 2010).

Excerpted from Malaria, Poems by Cameron Conaway. Copyright 2014 by Cameron Conaway. Excerpted by permission of Michigan State University Press. All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.

http://www.npr.org/blogs/goatsandsoda/2014/11/06/360469321/if-you-think-youll-never-see-a-poem-about-malaria-youre-wrong?utm_medium=RSS&utm_campaign=malaria

November 04 2014

rpiitpuapule

Drug-Resistant Malaria Spreads Across Southeast Asia



Yonta, 6, rests with her sister Montra, 3, and brother Leakhena, 4 months, under a mosquito net in the Pailin province of Cambodia — an epicenter of drug-resistant malaria. Paula Bronstein/Getty Images hide caption

itoggle caption Paula Bronstein/Getty Images

Yonta, 6, rests with her sister Montra, 3, and brother Leakhena, 4 months, under a mosquito net in the Pailin province of Cambodia — an epicenter of drug-resistant malaria.

Paula Bronstein/Getty Images

Back in 2008, doctors in Cambodia made a worrisome discovery. They were having a hard time curing some people of malaria.

Even the most powerful drug wasn't clearing out the parasite from patients' blood as quickly as it should. Malaria had evolved resistance to the last medicine we have against it, a drug called artemisinin.

Adam Cole/NPR/YouTube

What do Jesuit priests, gin and tonics, and ancient Chinese scrolls have in common? They all show up in our animated history of malaria.

At the time, scientists thought they might be able to keep this dangerous form of malaria from spreading, says biologist Carole Sibley, of the University of Washington.

"There has been a hope that we could keep drug-resistant malaria in the Pailin province of Cambodia," she says. "That you could launch a massive intervention, cast a ring around it and extinguish it."

Now all those hopes have been dashed.

A study published Wednesday in the New England Journal of Medicine found that artemisinin-resistant malaria is common throughout mainland Southeast Asia. It's cropped up in Thailand, Laos, Vietnam and Myanmar, an international team of scientists reported.

"The take-home message of the study is clear," says Sibley, who wasn't involved in the study. "Drug-resistant malaria hasn't stayed in Pailin."

Although there's no evidence yet that the dangerous type of malaria has spread outside Southeast Asia, scientists are looking for it in Africa and fear it could easily jump over to nearby India.

Artemisinin comes from a shrubbery plant, called sweet wormwood. The Chinese have used wormword extracts for thousands of years to treat fevers, and artemisinin drugs were highly effective in Cambodia for decades.

So why has the drug lost its potency recently?

Researchers aren't sure, says Dr. Christopher Plowe, of the University of Maryland School of Medicine, who contributed to the study. "But now that drug resistance has occurred, it seems to be spreading pretty rapidly."

It looks like the parasites in Southeast Asia have picked up a few mutations in their DNA that make it easier for them to evolve drug resistance, Plowe says.

It's like the parasites have a genetic predisposition for picking up resistance, he says, just like some people have a genetic predisposition for gaining weight or getting a specific type of cancer.

The good news, though, is that artemisinin can still cure nearly all malaria infections when it's mixed with other drugs. "It just takes longer to clear the parasite out of the blood [in some cases]," Plowe says. "Instead of taking a day or two after starting treatment, it can take up to four or five days," he says.

Artemisinin is the last approved drug that can cure any type of malaria around the world. But there are a few new medicines in the pipeline. One from the pharmaceutical company Novartis can clear the parasite from blood in about 12 hours, a preliminary study found.

"The new drug looks promising," Plowe says. "But it's only been tested in very small studies. So it will be some time before that's available."

http://www.npr.org/blogs/goatsandsoda/2014/08/05/336594646/drug-resistant-malaria-spreads-across-southeast-asia?utm_medium=RSS&utm_campaign=malaria

October 28 2014

rpiitpuapule

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http://blog.againstmalaria.com/syndication.axd?format=rss

October 21 2014

rpiitpuapule

396,900 nets on the way to Dowa District, Malawi



396,900 nets have shipped and will arrive in Dowa district in the middle of November for distribution from Dec14/Jan15 to protect 720,000 people and achieve universal coverage.

Our distribution partner Concern Universal will carry out the distribution.

AMF is funding both net and non-net costs, as was the case with the Balaka (2013) and Dedza (2014) distributions. We describe publicly the circumstances in which we cover non-net costs for a distribution.

A cost-driver led budget has led to detailed costings and we publish full budget details. Actual costs will be published at the end of the distribution.

The non-net cost per net is US$0.97. This covers shipping, pre-distribution activities (a district-wide household level registration to establish sleeping space net need), distribution and post-distribution follow-up (six, six-monthly check-ups of 5% of households, randomly selected and visited unannounced, carried out for three years post-distribution). 

http://blog.againstmalaria.com/post/2014/10/07/396900-nets-on-way-to-Dowa-District-Malawi.aspx

October 14 2014

rpiitpuapule

Which Contagious Diseases Are The Deadliest?



Do you know what the deadliest disease is? Hint: It's not Ebola (viral particles seen here in a digitally colorized microscopic image, at top right, along with similar depictions of other contagious diseases) NPR Composite/CDC hide caption

itoggle caption NPR Composite/CDC

Do you know what the deadliest disease is? Hint: It's not Ebola (viral particles seen here in a digitally colorized microscopic image, at top right, along with similar depictions of other contagious diseases)

NPR Composite/CDC

No one knows what the death toll in the Ebola epidemic will be. As of Tuesday, nearly 2,500 people have died and nearly 5,000 have caught the virus, the World Health Organization says.

So how does this epidemic compare with the toll taken by other contagious diseases?

Comparing fatality rates could help put the current Ebola outbreak in perspective. Trouble is, getting an accurate value for many diseases can be hard, especially in places where the health care infrastructure is weak.

Take the situation in West Africa right now. "We can only count those who come to the doctor, not those who stayed home and got well, or those who stayed home and died," says Carol Sulis, an epidemiologist at Boston University School of Medicine and the Boston Medical Center.

Another issue is that "deadliest" can mean two things. It can refer to the fatality rate — the number of deaths per number of cases — or it can mean the number of deaths in total caused by a disease.

What's more, diseases can take a different toll in different parts of the world. In low- and middle-income countries, only limited medical care may be available, if that. This will raise the fatality rate for many infectious diseases, such as tuberculosis, malaria and infectious diarrhea.

"Similar to Ebola, people's chances of survival increase for most of these [contagious] diseases, some dramatically, if people receive medical treatment," says epidemiologist Derek Cummings, at the Johns Hopkins Bloomberg School of Public Health.

Even if lists have their limitations, they can shed light. We spoke to Cummings and Sulis and consulted data from the World Health Organization and the U.S. Centers for Disease Control and Prevention to come up with two lists: the deadliest contagious diseases by death toll and by death rate if untreated.

Data are for all fatalities in 2012, except for infectious diarrhea and pneumonia. For those, death tolls represent a yearly estimate and represent childhood victims only.

Deadliest Contagious Diseases By Death Toll

Comparison point: As of Sept. 7, the number of reported deaths in the current Ebola epidemic is 2,218.

HIV/AIDS: 1.6 million deaths

Even though HIV takes a tremendous toll each year, the population of people living with the disease is about 35 million.

Since antiretroviral therapy — ART — became available in the mid-1990s, life expectancy for someone infected with HIV has dramatically increased. Today, a person who is promptly diagnosed with HIV and treated can look forward to a close-to-normal life span.

But as with other diseases, Sulas says, "we have to have the infrastructure to find the cases and be able to afford the medicine and deliver it to those affected."

Tuberculosis: 1.3 million deaths

Despite the death toll for this airborne disease, there is encouraging news: 7.3 million people developed TB and survived in 2012.

Recovery requires a regimen of several drugs over a six- to nine-month period. Patients who don't follow the drug schedule can develop drug-resistant TB. Drug-resistant forms of TB are also airborne. For those patients, treatment can extend to two years.

Pneumonia: 1.1 million children under the age of 5

It's the world's leading killer of children, "more than AIDS, malaria and tuberculosis combined," WHO says. The risks are also high for the elderly and those with other underlying conditions. In rich countries, like the U.S., vaccines can prevent the disease, but that is not the case in much of the world.

Infectious Diarrhea: 760,000 children under the age of 5

"That's an enormous waste," Sulis says. The majority of cases (about 1.7 billion globally each year) could be prevented and treated with better hygiene and sanitation, along with access to clean food and water. "There are many pathogens" that can cause these infections, she says, "but the whole class of diseases categorized as infectious diarrhea is deadly."

Malaria: 627,000 deaths

The world records about 200 million malaria cases each year. According to WHO, "most deaths occur among children living in Africa where a child dies every minute from malaria."

There's a growing worry for both malaria and TB, Sulis says, because "the organisms that cause those diseases are becoming increasingly drug resistant throughout the world."

Deadliest Contagious Diseases By Fatality Rate (If Not Treated)

Here, as in the list above, fatality rates can be lowered significantly depending on the presence of sanitary conditions and the availability of medical care and vaccines.

We present the diseases that appear to have the highest fatality rates if not treated. If the rate is a range, we ranked the disease by the highest possible fatality rate.

Comparison Point: Outbreaks of Ebola can have fatality rates up to 90 percent, WHO says. But in the current outbreak, it's about 50 to 60 percent.

Rabies is nearly 100 percent fatal if not treated. There are approximately 55,000 deaths each year, primarily in Asia and Africa.

Doses of the rabies vaccine after a bite from an infected animal will essentially abort the disease. But a person must receive treatment immediately. Initial symptoms include discomfort where the bite occurred, anxiety and agitation. Once clinical signs such as delirium and hallucinations arise, the patient almost always succumbs.

Creutzfeldt-Jakob disease is apparently 100 percent fatal.

This neurodegenerative disease rapidly progresses. It is caused by prions (nonviral, nonbacterial infectious agents that consist of a misfolded protein) that damage healthy brain tissue. Prions create holes in the brain that make it look like a sponge under the microscope.

CJD is classified as a contagious disease because it can be transmitted through contact with contaminated tissue during medical procedures. But it's not spread through the air or by casual contact.

No treatment exists for CJD. Its incidence is very low, affecting about 1 in 1 million people each year, with about 300 cases annually in the U.S. CJD can be difficult to diagnose because symptoms often resemble those of dementia and other diseases, with memory lapses, behavioral changes and sleep disturbances.

Marburg hemorraghic fever: 24 to 88 percent

Marburg is caused by a virus similar to Ebola, transmitted mainly by contact with bodily fluids from someone who's been infected. Fever, chills, headache and muscle pain are the first symptoms, showing up within five to 10 days after infection. The next stage can cause vomiting, diarrhea, delirium and organ dysfunction or failure. There's no known treatment beyond supportive hospital therapy. Since 1967, when Marburg was first recognized by scientists, there have been 571 reported cases.

H5N1 and H7N9 flu viruses: 60 percent for the former, 25 percent for the latter

These two viruses "remain two of the influenza viruses with pandemic potential," WHO says. They're in wide circulation among some groups of poultry; humans do not appear to have any immunity. The total number of human cases for both viruses so far is about 1,000. Some antiviral treatments and vaccines are available.

Middle East respiratory syndrome: 41 percent

First detected in 2012, this illness can lead to coughing, shortness of breath, fever and pneumonia. When patients die, the cause may be a lack of oxygen passing from the lungs into the blood. Scientists theorize that MERS could have first appeared in bats, which passed it to Arabian camels, which may then have infected humans. The majority of the 800 cases have been on the Arabian Peninsula.

http://www.npr.org/blogs/goatsandsoda/2014/09/16/347727459/which-contagious-diseases-are-the-deadliest?utm_medium=RSS&utm_campaign=malaria

October 05 2014

rpiitpuapule

Hiv May Have Emerged In Congo In 1920s - Wpfo Fox 23 | Maine, Local, News, Entertainment, Me

By Randy Dotinga HealthDay Reporter (HealthDay News) -- A new study into the origins of the AIDS virus suggests one strain of the disease appeared in the early 20th century in the western region of Congo and spread through a swath of Africa over the next several decades without notice by the rest of the world. The researchers say the findings support -- but don't prove -- the theory that the virus expanded its reach in Africa due to social factors such as railroad expansion, changing sexual habits and unsafe medical practices. The study adds to our understanding of "how a virus that is less transmissible than other pathogens like malaria and the common cold can still become established in the human population and eventually grow into a devastating pandemic," said study co-author Philippe Lemey, from the Rega Institute for Medical Research at Catholic University of Leuven, Belgium. "The fact that social changes were critical in the rise of the virus suggests that such changes may also be an important factor in combating epidemic spread," Lemey said. The origins of HIV, the sexually transmitted virus that causes AIDS, are still hazy. Scientists believe variations of the virus migrated from primates, possibly monkeys and chimps, to humans in Africa. Then two strains of the virus, known as HIV-1 and HIV-2, developed in people. The new study, published in the Oct. 3 issue in the journal Science, looks at a form of HIV-1, the prevalent strain in the world today. Scientists previously determined that it existed in heterosexual populations in the first half of the 20th century, but exactly where and when it appeared wasn't clear.
For the original version including any supplementary images or video, visit http://www.myfoxmaine.com/story/26689916/hiv-may-have-emerged-in-congo-in-1920s-study


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

September 30 2014

rpiitpuapule

A Fleet Of Weatherproofed Boats Stole The Spotlight At Clooney's Wedding

Great, you made it down here without collapsing. George Clooney, a man notorious for being handsome and desirable for all 53 years on His Earth, is now married to a woman who most agree is better than him , Amal Alamuddin. The pair had their intimate and obsessively photographed nuptials at the Aman Canal Grande in Venice, Italy on Saturday evening. To quote People magazine , "Congratulazioni!" to the happy couple. Pure, earnest love between a man who has malaria and a successful barrister and author will always be beautiful, but today it could never be quite as stunning or waterproof as the wedding's real stars: a mess of boats puttering about in the canals of Venezia. Molto bellissimo, Giorgio!
For the original version including any supplementary images or video, visit http://gawker.com/a-fleet-of-weatherproofed-boats-stole-the-spotlight-at-1639883991


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

September 26 2014

rpiitpuapule

An Authentic Genius Who Saved Thousands Of Lives | Albuquerque Journal News

But near the conclusion of his illustrious Sicilian campaign, the volatile Patton slapped two sick GIs in field hospitals, raving that they were shirkers. In truth, both were ill and at least one was suffering from malaria. Public outrage eventually followed the shameful incidents. As a result, Gen. Dwight D. Eisenhower was forced to put Patton on ice for 11 key months.
For the original version including any supplementary images or video, visit http://www.abqjournal.com/435835/riowest/an-authentic-genius-who-saved-thousands-of-lives.html

September 20 2014

rpiitpuapule

Malaria Identified As Cause Of Illness On Ship Docked In New Orleans | Nola.com

(AP Photo/David Goldman, File) View/Post Comments Federal health officials have identified malaria as the cause of an illness that hospitalized at least one crew member aboard a ship docked Wednesday evening in New Orleans. Jefferson Parish Councilman Chris Roberts said the Centers for Disease Control updated parish officials with the information Wednesday night, as at least one crew member of the Liberian-flagged ship, "Marine Phoenix," tested positive for the potentially fatal mosquito-born disease while at West Jefferson Medical Center. Two other ship occupants were also at West Jefferson, Roberts said. The CDC issued a statement late Wednesday saying that two other patients had "mild symptoms and are being assessed." The CDC did not disclose the nature of the crew member's symptoms. West Jefferson officials initially issued a statement saying that one of ship's crew members was in the hospital's care, and up to four crew members and the river pilot who boarded the ship could be on their way. "Our doctors and staff are ready and we have instituted full safety precautions in the unlikely event that this turns out to be something of concern," according to the hospital statement. The ship was on its way to the Jourdan Road Terminal in eastern New Orleans after finding a new river pilot, Roberts said. The Centers for Disease Control said the ship's previous stops included the port of Matadi in the Democratic Republic of Congo. It's a region that has experienced some reported cases of the deadly Ebola virus, but health officials initially said the chances of the ill crew member having Ebola are "exceedingly low." "There is no evidence to suggest that the crew members traveled to, or had any contact with anyone from the remote inland region of DRC where Ebola cases are occurring," according to a CDC statement. One of the ship's crew members fell ill and disembarked in the Bahamas two days ago, where according to the CDC he was diagnosed with malaria and later died.
For the original version including any supplementary images or video, visit http://www.nola.com/health/index.ssf/2014/09/ship_carrying_sick_crew_to_be.html


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

September 14 2014

rpiitpuapule

What You Need To Know About The Ebola Outbreak | Abc7.com

Health officials also suspect an "invisible caseload" in Liberia because new treatment facilities are filling with previously unidentified Ebola patients as soon as they open. Ebola Toll May 'Vastly Underestimate' Crisis US Hospitals and Colleges Taking No Chances Colleges will be screening students from West Africa for Ebola, according to the Associated Press . Some are testing students' temperatures and having private discussions with them about travel history. Hospitals and state labs across the country recently have reported dozens of possible Ebola cases to the U.S. Centers for Disease Control and Prevention.
For the original version including any supplementary images or video, visit http://abc7.com/news/what-you-need-to-know-about-the-ebola-outbreak/306634/


To read more about malarone malaria tablets please visit http://www.in.com/news/current-affairs/containing-ebola-outbreak-in-africa-is-us-priority-epidemic-could-worsen-obama-52931009-in-1.html

September 10 2014

rpiitpuapule

Guest: Ebola Just One Of Many Infectious Diseases Ravaging The World | Opinion | The Seattle Times

These diseases are infecting people around the globe at an alarming rate. Currently, more than 35 million people are living with HIV, and every minute, six people under the age of 25 are infected with the virus. Tuberculosis is a worldwide health crisis, and second only to HIV/AIDS as the largest killer worldwide due to a single infectious agent. In 2012, 8.6 million people contracted tuberculosis, and 1.3 million died from the disease. Even as the battle to combat Ebola in West Africa and prevent its spread continues, the public cannot lose sight of the much larger struggle against infectious disease being waged today. Whether global media cover it or not, every day millions of people around the world are suffering from infectious diseases that still have limited treatment options and no known cure. The current Ebola outbreak has captured the attention of the world. But as I, and others in my field know too well, this is just one small battle in the war against a deadly foe. Greater awareness of the horrific impact these diseases wage on communities, families, parents and children every day would help ensure that the public is able to sustain the commitment and resources needed to eradicate infectious diseases from the world once and for all.
For the original version including any supplementary images or video, visit http://seattletimes.com/html/opinion/2024500796_johnaitchisonopedebola10xml.html?syndication=rss


To read more about malarone malaria tablets please visit http://www.washingtonpost.com/world/national-security/obama-us-military-to-provide-equipment-resources-to-battle-ebola-epidemic-in-africa/2014/09/07/e0d8dc26-369a-11e4-9c9f-ebb47272e40e_story.html

September 06 2014

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Boston Doctor Infected With Ebola In Stable Condition - News, Weather And Classifieds For Southern New England

Sacra, a doctor from suburban Boston who spent 15 years working at the Liberia hospital where he fell ill, said he felt compelled to return after hearing that two other missionaries with whom he'd worked were sick. Sacra, who served with the North Carolina-based charity SIM, delivered babies at the hospital, and was not involved in the treatment of Ebola patients, so it's unclear how he became infected with the virus that has killed about 1,900 people. Dr. Phil Smith, medical director of the Omaha unit, has said a team of 35 doctors, nurses and other medical staffers will provide Sacra with basic care, including ensuring he is hydrated and keeping his vital signs stable. The team is discussing experimental treatments, including using blood serum from a patient who has recovered from Ebola, Smith said. There are no licensed drugs or vaccines for the disease, but about half a dozen are in development. Rupp said he's unaware whether Brantley and Writebol have been asked about donating blood serum for Sacra. "These folks are friendly and know one another, and they would presumably be willing to help their compatriots," Rupp said, adding a battery of tests must first be performed, including one to ensure that any blood serum is compatible with Sacra's blood type Much attention has focused on the unproven drug ZMapp, which was given to seven patients, two of whom died.
For the original version including any supplementary images or video, visit http://www.turnto10.com/story/26457107/boston-doctor-infected-with-ebola-arrives-in-nebraska


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

September 01 2014

rpiitpuapule

Magnetic Detection Of Malaria Shows Promise - Scientific American

Other available detection techniques are not quantitative and are expensive or impractical to use in the field, especially in developing countries. Jongyoon Han, a bioengineer at the Singapore-MIT Alliance for Research and Technology Centre, and his colleagues, have devised a diagnostic test that avoids many of those problems. Their method, described in a paper published on 31 August in Nature Medicine , works with a tiny droplet as little as 10 microlitres of blood, and can provide a diagnosis in just a few minutes. In addition, it does not rely on the expertise of a technician. WhenP. falciparuminvades red blood cells and feeds on their contents, it breaks down haemoglobin into amino acids and haem, a chemical compound that contains iron.
For the original version including any supplementary images or video, visit http://www.scientificamerican.com/article/magnetic-detection-of-malaria-shows-promise/


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August 27 2014

rpiitpuapule

Us Journalist Held Since 2012 Freed In Syria

In a statement released by the U.S. State Department,Curtis's family expressed gratitude to the U.S. and Qatar goverments and others who helped secure his release. "My heart is full at the extraordinary, dedicated, incredible people, too many to name individually, who have become my friends and have tirelessly helped us over these many months," said Curtis' mother, Nancy Curtis, of Cambridge, Massachusetts. Meanwhile, Britain said it is close to identifying a man, thought to be British, as the Islamic State fighter who beheaded American journalist James Foley as a protest against U.S.
For the original version including any supplementary images or video, visit http://www.voanews.com/content/britain-says-it-is-close-to-identifying-us-journalists-killer/2426506.html


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

August 22 2014

rpiitpuapule

Chikungunya Vaccine Performs Well In Early Clinical Trials - Health News - Redorbit

The candidate vaccine prompted a robust immunological response in recipients and was very well tolerated, noted Ledgerwood. Notably, the levels of neutralizing antibody produced in response to the experimental vaccine were comparable to those seen in two patients who had recovered from a chikungunya virus infection acquired elsewhere. This observation gives us additional confidence that this vaccine would provide as much protection as natural infection. The new vaccine is different from most typical vaccines because, rather than being made from killed viruses or weakened live viruses, this one is created from a virus-like particle (VLP) developed from the outer structural proteins of the West African strain 37997. Vaccines created from VLPs usually prompt an immune system reaction similar to that of natural, whole virus exposure. Dr.
For the original version including any supplementary images or video, visit http://www.redorbit.com/news/health/1113214204/chikungunya-vaccine-clinical-trial-081814/


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

August 21 2014

rpiitpuapule

Novartis Hands Over Experimental Tb Drugs In Antibiotic Pullback - Yahoo News

The TB Alliance deal reflects renewed scrutiny of the Novartis portfolio under new chairman Joerg Reinhardt, who is focusing the Swiss company's research on core areas such as cancer, respiratory drugs, heart failure and dermatology. While scientists are exploring novel avenues in the hunt for urgently needed new bacteria-fighting medicines, many companies now have little appetite for the chase, preferring to concentrate on more lucrative areas such as cancer and diabetes. "Novartis is not really focused on anti-infectives, so I think it makes sense," Kepler Cheuvreux analyst Fabian Wenner said of the licensing deal. Under the terms of Wednesday's agreement, TB Alliance will fund further research and development and be responsible for seeking approval and commercializing the TB treatments discovered at the Novartis Institute for Tropical Disease. NO UPFRONT PAYMENT "The goal of this agreement is to enable the program to be successful and bring needed medicines to patients," Novartis said in an emailed statement, adding that it had not asked for any upfront or milestone payments. Among the drugs Novartis is licensing is a class of medicines known as indolcarboxamides, which target drug resistant and multi-resistant strains of TB. One of the compounds, NITD304, works by blocking a protein that is essential for the TB bacterium's survival.
For the original version including any supplementary images or video, visit http://news.yahoo.com/novartis-hands-over-experimental-tb-drugs-antibiotic-pullback-122414163--finance.html


To read more about malarone malaria tablets please visit http://www.malariaprevention.co.uk/malarone-atovaquone-proguanil/

August 11 2014

rpiitpuapule

The Roots Of Our Ebola Fears - Cnn.com

The virus infects, say, a chimp or gorilla, and a human who has close contact with that animal becomes infected. Coming into contact with, or eating, the types of animals that become infected with Ebola would be a highly unusual scenario in the United States -- as unusual as mass human-to-human infection. Still, ambivalence is not the attitude we should have when it comes to diseases such as Ebola, says Wald, the "Contagious" author. We should have some level of deference to Ebola's virulence; it kills between 60% to 90% of the people it infects. At the same time, it must be acknowledged that becoming infected is difficult. "Should you be scared?
For the original version including any supplementary images or video, visit http://www.cnn.com/2014/08/06/health/ebola-epidemic-fears/index.html

July 28 2014

rpiitpuapule

Gsk Seeks Regulatory Ok For World's First Malaria Vaccine - Upi.com

According the World Health Organization, the parasite infected 207 million people in 2012. Some 627,000 of those infected perished. Humans become infected with the disease via mosquitos which carry the parasite and transfer it when they bite. "This is a key moment in GSK's 30-year journey to develop RTS,S," said Sophie Biernaux , head of the company's malaria vaccine program. "And brings us a step closer to making available the world's first vaccine that can help protect children in Africa from malaria." Most of the world's malaria cases occur in Sub-Saharan Africa, but peoples of the tropics all over the globe are at risk. The CDC refers to the disease as "one of the most severe public health problems worldwide." The malaria parasite, which spawns the disease, produces more than 5,000 proteins during its lifetime, making it exceedingly difficult for researchers trying to figure which one to mimic in order to trigger an effective immune response from the body. But scientists seemed to have finally located a combination of proteins that works, and if the EMA offers their approval, the drug will soon be available to some of the world's most vulnerable populations. RTS,S has shown promise in trials ever since its earliest development in the 1990s.
For the original version including any supplementary images or video, visit http://www.upi.com/Health_News/2014/07/24/Company-seeks-regulatory-approval-for-first-ever-malaria-vaccine/3001406233973/

July 19 2014

rpiitpuapule

Health Aware: Clinic Offers Better Shot At Healthy Travel | Naperville Sun

Kathleen Kelley, medical director of the Edward Travel Medicine Clinic, prescribed medication to limit altitude sickness. Unlike some members of the climb, Bergamini developed no symptoms of this potentially dangerous condition. Bergamini checked in with the clinic again in preparation for a summer 2014 trip to South America. She found she already was covered regarding vaccinations. And she didnt need the anti-malarial medications she took for an earlier South American trip because the new itinerary did not include the same malaria hot spots. As a medically run travel clinic, we take into account the patients chronic medical conditions, medications and allergies before making our recommendations, Dr.
For the original version including any supplementary images or video, visit http://napervillesun.suntimes.com/2014/07/16/health-aware-clinic-offers-better-shot-healthy-travel/

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